The NKp46/NCR1 Antibody from MyBioSource.com is a Mouse Monoclonal antibody. This antibody recognizes Human antigen. The NKp46/NCR1 Antibody has been validated for the following applications: ELISA, and Flow Cytometry.
Description
A natural cytotoxicity receptor (NCR), Nkp46, is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 residue stalk resion, a type I transmembrane domain, and a short cytoplasmic tail. Nkp46 has been shown to represent a novel Nk cell-specific molecule involved in human Nk cell activation. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. Nkp46 has been implicated in Nk cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines